diff --git a/patroni/postgresql/config.py b/patroni/postgresql/config.py
index eb981cd8..a7d46db3 100644
--- a/patroni/postgresql/config.py
+++ b/patroni/postgresql/config.py
@@ -618,19 +618,19 @@ class ConfigHandler(object):
 
     def _check_passfile(self, passfile, wanted_primary_conninfo):
         # If there is a passfile in the primary_conninfo try to figure out that
-        # the passfile contains the line allowing connection to the given node.
+        # the passfile contains the line(s) allowing connection to the given node.
         # We assume that the passfile was created by Patroni and therefore doing
         # the full match and not covering cases when host, port or user are set to '*'
         passfile_mtime = mtime(passfile)
         if passfile_mtime:
             try:
                 with open(passfile) as f:
-                    wanted_line = self._pgpass_line(wanted_primary_conninfo).strip()
-                    for raw_line in f:
-                        if raw_line.strip() == wanted_line:
-                            self._passfile = passfile
-                            self._passfile_mtime = passfile_mtime
-                            return True
+                    wanted_lines = self._pgpass_line(wanted_primary_conninfo).splitlines()
+                    file_lines = f.read().splitlines()
+                    if set(wanted_lines) == set(file_lines):
+                        self._passfile = passfile
+                        self._passfile_mtime = passfile_mtime
+                        return True
             except Exception:
                 logger.info('Failed to read %s', passfile)
         return False
@@ -745,7 +745,12 @@ class ConfigHandler(object):
                 return re.sub(r'([:\\])', r'\\\1', str(value))
 
             record = {n: escape(record.get(n) or '*') for n in ('host', 'port', 'user', 'password')}
-            return '{host}:{port}:*:{user}:{password}'.format(**record)
+            # 'host' could be several comma-separated hostnames, in this case
+            # we need to write on pgpass line per host
+            line = ''
+            for hostname in record.get('host').split(','):
+                line += hostname + ':{port}:*:{user}:{password}'.format(**record) + '\n'
+            return line.rstrip()
 
     def write_pgpass(self, record):
         line = self._pgpass_line(record)